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Send this info to a friend To: Check this box if you wish to have a copy Plavix best Buy to you. We won’t use your friend’s e-mail for Plavix best Buy other than sending this message. See our privacy policy. But more doctors have been using an initial, higher-than-standard dose of clopidogrel to boost its efficacy, and how that regimen stacks up against prasugrel on key clinical outcomes is unclear.
Deciding who is likely to be helped—or harmed—by the Plavix best Buy options requires Plavix best Buy consideration of many factors. Acute coronary syndrome—either unstable angina escalating heart-related chest pain or a heart attack in progress—is often treated by percutaneous coronary intervention PCI, or angioplasty, in which cardiologists inflate a tiny balloon inside a blocked artery. To help prevent blood clots that can block the artery again after the procedure, doctors prescribe medication that inhibits the action of platelets, or clot-forming blood cells, Plavix Best Buy.
The body converts prasugrel to its active form considerably faster than it does clopidogrel. Indeed, the approved, 300-mg dose of clopidogrel takes hours to reach full strength—a potentially significant drawback during a coronary crisis, Plavix Best Buy.
Moreover clopidogrel, at smallbevy.com elsewhere.
Making the decision While further study is clearly needed, some general guidelines can be offered based on what’s currently known. Prasugrel plus aspirin may be a sensible choice for coronary syndrome patients who are undergoing PCI, have no risk factors for bleeding, and get to the hospital early enough for doctors to determine whether they might need bypass surgery instead. In contrast, patients with a history of strokes or transient ischemic attacks should avoid prasugrel.
Studies so far have not linked clopidogrel, at least at the approved dose, with increased risks for those patients.
People age 75 or older should probably stick with clopidogrel in most cases, particularly Plavix best Buy prasugrel is not www.autogm.it weigh Plavix best Buy than about 130 pounds, Plavix Best Buy, the package insert says that doctors could consider halving the maintenance dose of prasugrel; although, there is no direct evidence that this smaller dose is actually safer or as effective. Those who need bypass surgery should not take prasugrel or, if they’ve already started, should stop Plavix best Buy it at least a week before their operation.
Clopidogrel should generally be stopped five to seven days before surgery. An increased hemorrhage risk from prasugrel seems to make clopidogrel more desirable, while the high risk of clotting favors prasugrel or the doubled dose of clopidogrel.
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Factors that may make generic Sinequan more likely include previous clotting problems, heart disease, diabetes, small blood vessels, and the placement of multiple stents, the tiny metallic mesh tubes that prop open PCI-treated vessels, Plavix Best Buy. In general, Consumer Reports medical consultants recommend against using prasugrel for unapproved uses, such as for the prevention of a second heart attack. That would be particularly reasonable if doctors can test for platelet responsiveness to clopidogrel. If your doctor recommends prasugrel even Plavix best Buy you have risk factors for bleeding, ask for a Plavix best Buy explanation and, if Plavix best Buy, seek a second opinion if you’re not satisfied.
Do the same if he or she recommends an off-label use of prasugrel. If you’re already using prasugrel or clopidogrel, take these precautions: Call your doctor immediately if you notice any signs of excessive bleeding that can’t be explained: But don’t stop taking the medication without your doctor’s OK.
Use an Plavix best Buy razor or be extra careful when shaving. If you’re taking clopidogrel or a smaller than recommended dose of prasugrel, consider asking your doctor if you should be tested for adequate platelet inhibition.